Shelagh Stephenson’s 1996 debut, “The Memory of Water,” is wise and witty, and spins a delicate treatise on human nature with gentleness and precision.Running through Oct. 30, the play begins Piccolo Theatre’s 16th season as the first of four productions celebrating women in theatre and finding humor as healing in unexpected places.

Leavened with humor, this drama makes statements about death, dying, and memory while remaining alive and lively due in large part to its actor-driven storytelling by women. The title refers to homeopathy – the way water “remembers” healing properties.

Stephenson suggests brains work similarly, saving what they need to keep a person going; that any self-centricity is rooted in vulnerability.

“The Memory of Water” runs Fridays and Saturdays at 8 p.m. and Sundays at 3 p.m. at Piven Theatre Workshop, 927 Noyes St. Tickets are available through the Piccolo Theatre Box Office, 847-424-0089, Tuesday-Friday 10 a.m.-5 p.m., and one hour prior to the scheduled showtimes.